THE PERIOPERATIVE USE OF CEFTRIAXONE AS INFECTION PROPHYLAXIS IN NEUROSURGERY: CRANIOPLASTY

Abstract

Author(s): Amer Hayat Khan*, Andee Dzulkarnaen Zakaria, Syed Azhar Syed Sulaiman, Muhammad Ihtisham Umar,Nur-Elyana Yazmin Redhuan

Prophylactic use of antibiotics applied peri or intraoperatively is commonly adopted in many hospitals to decrease the incidence of postoperative infections following surgery, including neurosurgery. We report a case of a 20 years old young female who undergone cranioplasty. A year earlier, the subject underwent removal of bone flap after a motor-vehicle-accident. It resulted into the development of a sinking skin flap, insisting a cranioplasty immediately after 6 months that was delayed, however, for one year. The patient was given a course of antibiotic prophylaxis of IV Ceftriaxone 2gram stat pre-surgery and continued with IV Ceftriaxone 1 gram for another 2 doses. No infection was developed in the subject several days after the surgical procedure, proving it to be successful. The current case study encouraged the prophylactic use of antibiotics to prevent sepsis or infections associated with cranial surgeries.