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ISSN (Online) : 2277-4572

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SCHIFFS BASES

Abstract

Author(s): Omran Fhid*, Talal Zeglam, Asma Gebril

Keeping in view of the biological potential of Schiff bases attached to heterocyclic ring system; a series of novel Schiff's base derivatives were synthesized 1-8 successfully in appreciable yields. The structures of all the synthesized derivatives were confirmed by physical and spectral analysis. Furthermore, all synthesized compounds were evaluated for antifungal activity against different strains of fungal organisms. Some of the compounds exhibited appreciable antifungal activity comparing to the reference compound (Nystatine).