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ISSN (Online) : 2277-4572

POTENTIAL PHYTOTHERAPEUTIC AGENTS IN DESIGN OF ETHOSOMES: A REVIEW

Abstract

Author(s): Anju Dhiman

Transdermal drug delivery is one of the efficient methods in novel drug delivery system. Skin is a major target as well as a principle barrier for transdermal drug delivery. The major disadvantage of this system is low diffusion rate of drug(s) across stratum corneum. Ethosomes are modified lipid carriers that enables drug to reach deep into the systemic delivery system. Ethosomes are soft, malleable vesicles embodying alcohol in relatively higher concentration and efficient in delivering drug across the skin. The present review is an attempt to overview the applications of ethosomal formulations and various herbal options (plants or their active therapeutic principles) that may be explored further in the form of ethosomes for treating various types of skin ailments v.i.z. itching , eczema , leucoderma , scabies and other skin diseases.