HEPATOPROTECTIVE ACTIVITY OF EUPHORBIA HIRTA LINN. PLANT AGAINST CARBON TETRACHLORIDE -INDUCED HEPATIC INJURY IN RATS

Abstract

Author(s): Dubey Subodh Ù­ 1 , Mehta S. C.2

Ethanolic extract of Euphorbia hirta Linn was prepared and tested for its hepatoprotective effect against CCl4-induced hepatitis in rats. Alteration in the levels of biochemical markers of hepatic damage like SGPT, SGOT, ALP, bilirubin, were tested in both treated and untreated groups. Carbon tetra chloride (2 ml/kg) has enhanced the SGPT, SGOT, ALP and bilirubin. Treatment with Ethanolic extract of Euphorbia hirta Linn (100 mg/kg and 300 mg/kg) has brought back the altered levels of biochemical markers to the near normal levels in the dose dependent manner