EFFECT OF CARROT AND GINGER EXTRACTS (ALONE AND IN COMBINATION WITH CIPROFLOXACIN) ON MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA

Abstract

Author(s): Al-Alak, Shaymaa Khudhr; Ali, Wala’a Shawkat*; Kadum, Maha Mikhlef and Othman, Nabaa Abd-Alkhalik

Antibacterial activity of ginger (Zingiber officinale) and carrot (Daucus carota) watery extracts (cold and hot) with or without ciprofloxacin against 53 isolates of multidrug- resistant Pseudomonas aeruginosa was screened by agar well diffusion method. The results showed that the hot watery extracts were more active than cold watery extracts. The combination of ciprofloxacin and hot watery extracts of ginger or carrot was most effective than ciprofloxacin alone or plant extracts alone, also the results showed that the mixture of ciprofloxacin and ginger extract was the best for inhibition growth of P. aeruginosa. These results indicate that the plant extracts contain natural inhibitors and the combination between them and ciprofloxacin could be useful in fighting emerging drug-resistance P. aeruginosa.