A PHARMACEUTICAL APPROACH OF MANIKYA BHASMA TOWARDS ITS STANDARDIZATION

Abstract

Author(s): Wavare Ramesh, Yadav Reena*, Sheth Suchita, Sawant Ranjeet

Manikya [Ruby] is one of the nine gems described in Ayurveda texts comprising of Aluminum oxide, chromium and Titanium. Manikya Bhasma [MB] is one of the exceptional preparations mentioned in Rasashastra texts. It is having innovate action on various hormonal, enzymatic, immunological pathways, as it comprises main stream trace elemental moieties. The Objective of the study was to prepare MB and standardize it with different physico-chemical parameters. Two types of Manikya bhasma were prepared i.e. Hartaladi Manikya Bhasma [MB1] and Vanaspati (gulab jal marit) Manikya Bhasma [MB2] as per textual reference with the help of 8 puta (ancient heating procedure). Prepared bhasma was subjected to ancient as well as modern physico-chemical analysis mainly XRD, DLS, Microscopic examination and results were compared. XRD Result of Raw Ruby showed Al2O3 as principal component. Mean Particle Size of Raw Ruby is 1071.58 nm. The particle sizes of MB1 and MB2 were respectively 43 nm and 63 nm. So it can be concluded that both MB1 and MB2 are nanomedicine, hence both will have better assimilation in human body